Detalhe da pesquisa
1.
Discovery of potent BET bromodomain 1 stereoselective inhibitors using DNA-encoded chemical library selections.
Proc Natl Acad Sci U S A
; 119(22): e2122506119, 2022 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35622893
2.
Palladium-Catalyzed Hydroxycarbonylation of (Hetero)aryl Halides for DNA-Encoded Chemical Library Synthesis.
Bioconjug Chem
; 30(8): 2209-2215, 2019 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31329429
3.
Benzofuran-pyran hybrids: A new class of potential bone anabolic agents.
Bioorg Med Chem Lett
; 28(10): 1719-1724, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29703629
4.
Benzofuran-dihydropyridine hybrids: A new class of potential bone anabolic agents.
Bioorg Med Chem
; 25(24): 6450-6466, 2017 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29097030
5.
Design and synthesis of new series of coumarin-aminopyran derivatives possessing potential anti-depressant-like activity.
Bioorg Med Chem Lett
; 25(2): 337-41, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25488839
6.
Synthesis and evaluation of new 3-phenylcoumarin derivatives as potential antidepressant agents.
Bioorg Med Chem Lett
; 24(20): 4876-80, 2014 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25239852
7.
Discovery of Highly Potent and BMPR2-Selective Kinase Inhibitors Using DNA-Encoded Chemical Library Screening.
J Med Chem
; 66(3): 2143-2160, 2023 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36719862
8.
Antiplasmodial activity of novel keto-enamine chalcone-chloroquine based hybrid pharmacophores.
Bioorg Med Chem
; 20(9): 2971-81, 2012 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22464685
9.
Discovery and synthesis of novel substituted benzocoumarins as orally active lipid modulating agents.
Bioorg Med Chem Lett
; 21(22): 6709-13, 2011 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21983443
10.
Synthesis and anti-inflammatory activity of novel biscoumarin-chalcone hybrids.
Bioorg Med Chem Lett
; 21(15): 4480-4, 2011 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21723119
11.
Development of Leishmania donovani stably expressing DsRed for flow cytometry-based drug screening using chalcone thiazolyl-hydrazone as a new antileishmanial target.
Int J Antimicrob Agents
; 48(6): 695-702, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27876275
12.
Novel Chalcone-Thiazole Hybrids as Potent Inhibitors of Drug Resistant Staphylococcus aureus.
ACS Med Chem Lett
; 6(7): 809-13, 2015 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26191371
13.
Synthesis and antifilarial activity of chalcone-thiazole derivatives against a human lymphatic filarial parasite, Brugia malayi.
Eur J Med Chem
; 81: 473-80, 2014 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24863844
14.
Discovery of 3-Arylcoumarin-tetracyclic Tacrine Hybrids as Multifunctional Agents against Parkinson's Disease.
ACS Med Chem Lett
; 5(10): 1099-103, 2014 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25313319
15.
Benzofuran-chalcone hybrids as potential multifunctional agents against Alzheimer's disease: synthesis and in vivo studies with transgenic Caenorhabditis elegans.
ChemMedChem
; 9(12): 2671-84, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25251917
16.
Hybrid benzofuran-bisindole derivatives: new prototypes with promising anti-hyperlipidemic activities.
Eur J Med Chem
; 68: 38-46, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23954239
17.
Synthesis and evaluation of new coumarin-pyridine hybrids with promising anti-osteoporotic activities.
Eur J Med Chem
; 70: 802-10, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24246729
18.
Discovery of coumarin-dihydropyridine hybrids as bone anabolic agents.
J Med Chem
; 56(1): 109-22, 2013 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-23214410